ALOPECIA
(HAIR LOSS)
Different forms of alopecia can be differentiated. Autologous blood therapies have shown to be effective especially in androgenetic alopecia and alopecia areata.
ALOPECIA
TREATMENT OF ANDROGENETIC ALOPECIA (AGA) & ALOPECIA AREATA (AA)
Androgenetic alopecia (AGA) and alopecia areata (AA) belong to the most prevalent types of progressive hair loss. Although standard of care treatments* show satisfying effects in AGA and AA, they require long-term treatment and involve the risk of potential side effects. Novel, more effective and faster-acting therapeutic strategies are therefore needed. Autologous blood therapies have been shown to be a very promising alternative with vast therapeutic effects in hair loss.
The 3 stages of hair growth:
PRP and ACS in hair loss
Both, AA and AGA are characterzed by dysregulation of the hair cycle and the signaling pathways associated with it. The hair cycle is a carefully coordinated physiologic pattern consisting of broadly three phases of hair growth, being heavily dependent on multiple signaling pathways. Moreover, it is presumed that all hair loss conditions may have an underlying chronic inflammation at the follicle level (micro-inflimmation). Therefore, in addition to PRP, autologous blood therapies such as ACS, which are known to be particularly effective in treating inflammatory conditions, are a favourable option for the initial phase of treatment with autologous blood therapies.
EFFECTS OF AUTOLOGOUS BLOOD THERAPIES
The multifactorial nature of autologous blood therapies can help address multiple signaling pathways that may be dysregulated in alopecia conditions. There are a number of growth factors and cytokines discharged through PRP that can help counteract the dysregulation associated with alopecia conditions or establish a permissive microenvironment for healthy hair follicles to take root.
As a result, treatment with autologous blood therapies is likely to reduce hair loss, increase hair diameter and density in patients with alopecia. Recent clinical trials even suggest that regenerative therapies as PRP or ACS are more effective and more rapidly-acting than compared standart of care treatments*. (*namely: minoxidil, finasteride)
